Psyllium husk in powder form becomes much more effective, hence it is desired to use it in finer particle size. Isabgol has been popularly used as a therapeutic agent for the treatment of constipation, diarrhoea, irritable syndrome, inflammatory bowel disease, ulcerative colitis, colon cancer, diabetes, and hypercholesterolemia. It is considered to be a mild and natural laxative which facilitates digestion. It becomes gelatinous and sticky when soaked in water and absorbs water to perform characteristic functioning. Psyllium husk may help in weight management and fat loss by acting as bulking agent. It improves glucose homeostasis and lipid & lipoprotein profile in obese and hypercholesterolemic subjects. Isabgol is a natural edible polymer to be used in haemorrhoids, constipation, diabetes, ulcerative colitis. Besides its traditional use in constipation, husk can lower down the abnormal LDL level up to the normal which is the causative factor for different problems eg. Hypercholesterolemia, hypertension, low body working efficiency etc.

All of the therapeutic applications of Isabgol are with negligible side effects/ or adverse effects. Therefore, it is not only a laxative agent but also a true soluble dietary fibre source with hypocholesterolemic and hypoglycemic perspectives. Psyllium fiber supplements alone or with a healthy diet significantly reduced body weight, percentage of total body fat and BMI. Moreover, it has a significant role in lowering triglycerides and insulin levels after 12 weeks of psyllium consumption. The diet enriched with fibre significantly reduced total cholesterol and LDL which ultimately declines metabolic syndrome risk factors.

Different cereal and vegetable based soluble and insoluble fibres are in use to overcome the menace of high cholesterol and glycemic disorders. The foremost fibre sources are psyllium husk, oat, guar gum and some other cereals. However, psyllium husk fibre appears to be one of the effective sources with least adverse effects. It contains high water soluble fibre that soothes the lipid and glycemic response in individuals with hypercholesterolemia. Due to neutral and acid polysaccharides containing galacturonic acid with an appropriate ratio of soluble/insoluble fibre in contents Psyllium husk has anti-obesity properties. Different investigations indicated that psyllium husk supplementation results in reduction of postprandial glucose level ranging from 12.2 to 20.2% in diabetic patients. In hypercholesterolemic children, psyllium lowers serum LDL and triglycerides concentration up to 22.81 and 19.54% respectively, whilst increases HDL up to 3.05%. Some of the impacts as laxative can be due to its bioactive components, namely phenolic compounds such as acetoside and isoacetoside. Antidotal and antioxidant activities besides being painkillers are among their biological functions.

The so called properties have made psyllium a suitable functional dietetic fibre to use in some food products. It can be used as a bioactive oligosaccharide with probiotics. Psyllium is well accepted as a safe and effective bulk laxative and is an adjunct to dietary intervention for individuals who do not adequately respond to a low-fat, low-cholesterol diet.